In medicinal chemistry, hard drugs refer to compounds that are generally nonmetabolisable. SAR studies explore the relationship between a molecule’s biological activity and the three dimensional structure of the molecule. Free proofreading and copy-editing included. That’s about it for our medicinal chemistry glossary. Removal is generally through hydrolysis. An example of a buffer is acetic acid and sodium acetate. In QSAR, Hansch analysis expresses biological activity using electronic, hydrophobic, and steric parameters. chlorofluorocarbon - A chlorofluorocarbon or CFC is a compound that contains atoms of chlorine, fluorine, and carbon. 6. Medicinal Chemistry Glossary. Attractive non-covalent interactions that arise between aromatic rings. In chemical synthesis, yield refers to the amount of product obtained at the end of a chemical reaction. How to use chemistry in a sentence. In analytical chemistry, quantitative analysis is the determination of the presence or absence of a substance in a sample. •absolute temperature: This is a temperature reading made relative to absolute zero. Regions in a drug target where an endogenous ligand or drug can bind. An official documentation which details the analytical procedures, effects and directions of use of medicinal substances. To see Science word lists , please go to the home page for word games, interactive worksheets, word puzzles and themed content with Latin roots that align with Common Core Standards. A-Z Chemistry definitions for use with A-Level Chemistry Our database of chemistry definitions provides key information and a summary of many chemistry terms, covering them in enough detail to help you fully understand the terms in preparation for your A-Level Chemistry exams. Chemical symbol – A short form used to represent the name of an element; C is the chemical symbol for carbon. Drugs that are covalently linked to antibodies. The use of molecular modelling software packages to design new drugs or lead compounds for binding sites. Used during the characterisation of molecules. Not all orally active drugs obey the rule. It consists of a nucleus which is surrounded by a cloud of electrons. A unit of measurement for temperature. One purpose is to enhance drug site-specificity. Metal – Typically, an element that is solid at room temperature, shiny, malleable, ductile, and a good conductor; for example, aluminum, iron, and calcium. Attractive interactions involving two groups: one containing an electron-deficient hydrogen covalently bonded to an electronegative atom and one containing an electron-rich heteroatom. A branch of chemistry that is concerned with the study of the relationship between chemical properties and the spatial arrangement of atoms and molecules in a compound. Periodic Table – A system for organizing the elements into columns and rows, so that elements with similar properties are in the same column. From the textbook Physical Science, (Glencoe Science made) Chapters 15-21 excluding 18. In molecular modelling, docking refers to the process by which molecules fit into a binding site. Bioisosteres are chemical groups with similar physicochemical properties which give broadly similar biological properties to a compound. 10. Severe allergic reaction that can cause intensely itchy welts (hives) on the skin, low blood pressure, and difficulty breathing. 28. A form of liquid chromatography used in analytical chemistry used to separate, identify, and quantify the components of a mixture. DFT computational approaches consider that the energy and other properties of a system can be computed from the electron density. 23. Experimental determination of heat changes arising from chemical or physical change. Decomposition – A kind of reactivity that can break down a substance into its parts; for example, water can be broken down into hydrogen and oxygen by decomposition. students – all of whom vouch for the high-quality learning materials. https://schoolworkhelper.net/general-chemistry-key-terms-definitions/, Titration Lab: NaOH with Standardized solution of KHP, Reaction rate of Hydrochloric Acid and Limestone: Experiment Results, Decomposition of Hydrogen Peroxide Lab Answers, Hydrogen Peroxide Breakdown in Liver vs. Select the first letter of the chemistry term you need a definition for: Some common chemistry terms: Element - A substance that cannot be decomposed into simpler substances. Please enter username and password bellow! We use the unit of Kelvins for these readings. A charge or a dipole can induce a dipole in another molecule. A branch of chemistry that specialises in using computers to help solve chemistry problems. A chemical entity that contains both anionic and cationic groups. The functional group that contains the electron-deficient hydrogen covalently bonded to an electronegative atom. In an element, all the atoms have the same number of protons or electrons although the number of neutrons may vary 12. It is the study of the materials that make up our bodies and everything in the world around us. ATTENTION: Please help us feed and educate children by uploading your old homework! Usually in chemistry the term is used to describe a pair of molecules that have the same formulas, but form a pair of structures. For example, the CN of Pt and Ni in the complex ions [PtCl6]2– and [Ni(NH3)4]2+are 6 and 4, respectively. Groups introduced during drug design to prevent a molecule from adopting particular conformations. Atom – the smallest unit of an element that displays the same properties as the element, for example, hydrogen. Electron – A particle of an atom that surrounds the nucleus; has a charge of negative one. Author: Jonny-Ringo. The use of simpler analogues eases synthesis. Tutor and Freelance Writer. Neutron – Located in the nucleus of an atom, has no charge. An automated method of performing large amounts of. An analytical technique that takes advantage of the magnetic properties of certain nuclei. A List of Basic Chemistry Apparatus. A sour substance which can attack metal, clothing or skin. In chemistry, often refers to situations where a molecule adheres to a surface. Prodrugs that are activated by oxidation or reduction processes rather than simple hydrolysis. Science, English, History, Civics, Art, Business, Law, Geography, all free! Below, you will find the neurotransmitter serotonin – try to identify all the structural features of this molecule. 20. The latter half of the medicinal chemistry glossary focuses on structural aspects of organic chemistry; a convenient revision resource for those studying sciences with a significant chemistry component. Interactions that occur between molecules. 9. Can be used to inhibit an enzyme, Ultraviolet–visible Spectroscopy (UV-Vis). In the simplest sense, drug targets are macromolecular biomolecules such as proteins whose activity can be altered by a pharmacologically active compound. High Performance Liquid Chromatography (HPLC). There are many words and terms that are specific to chemistry, in this case inorganic chemistry. Glossary Of Chemistry from skool.ie. Try to use this medicinal chemistry glossary as a convenient revision – tying up loose ends whenever you need to refresh your memory. NIST and the Nobel: Dan Shechtman. Basic Chemistry Vocabulary List. In coordination chemistry, ligands are ions, molecules, or functional groups that bind to a central metal atom, forming a coordination complex. Let us do your homework! The active principle is the compound(s) in the mixture that is responsible for that mixture’s biological activity. This is a list of the 118 chemical elements which have been identified as of 2021. A compound that is structurally related to another. 1. An online dictionary of AP Chemistry terms that you will need to know for the AP Chemistry Exam. Chemical groups added to a drug that slow down or block metabolism at that part of the drug. Chemistry: terms used in chemistry: acid, alcohol, alkali, alkali metal, alkaline earth metal | Collins English Word Lists In chemical terms; expression of the proportional relationship between response and concentration over a defined range. Chemistry is a branch of science that explores compounds and chemical elements, and how they work together. Chemical reaction – Any change that occurs when substances interact to produce new substances with new properties; changes in the chemical and physical properties of the pure substances let you know that a chemical reaction has occurred; when vinegar and baking soda are combined, they react to produce frothy bubbles. In terms of nuclear chemistry, half-life refers to the time taken for a radioisotope to fall to half its original value. Proteins which ligands can bind to and elicit a biological response. Combustibility – The ability of a substance to catch fire and burn in air. Large biological molecules (mostly proteins) that act as catalysts for a reaction. Covering structural features such as functional groups, cyclic aliphatic compounds, and heterocycles found in organic compounds that are used as drugs – this medicinal chemistry glossary is the complete resource for your studies. 27. Chemical formula – A short form used to represent a molecule; uses letters and numbers; only pure substances have chemical formulas; H2O is the chemical formula for water. An organism’s complete set of genetic information. List of Chemistry Terms You can browse Chemistry Dictionary by using the A-Z listing below. A highly selective permeability barrier that prevents many compounds from reaching the brain. Here is a list of some of the most common and most interesting terms you need to know. Short for enzyme-linked immunosorbent assay, an immunochemical test often employed in the biochemical sciences. Particles with sizes ranging from 1 – 100 nanometres. The latter half of the medicinal chemistry glossary focuses on structural aspects of organic chemistry; a convenient revision resource for those studying sciences with a significant chemistry component. The chemical opposite of an alkali. Chemical modifications done by an organism on chemical compounds. Cite this article as: William Anderson (Schoolworkhelper Editorial Team), "General Chemistry: Key Terms & Definitions," in. Refers to non-polar molecules that have little affinity for water. Me-too drugs are often developed by rival pharmaceutical companies in order to gain a foothold in the same area of the market. A compound is said to be xenobiotic if it is foreign to an organism. In lay terms, often referred to as a "test." A binding site is said to be allosteric if it’s a binding site other than the one used by the endogenous ligand. Proton – A particle of an atom that is inside the nucleus; has a positive charge. A compound that has not been previously described in the scientific literature. The study of the processes by which ligands interact with their binding site and the biochemical and physiological changes associated with the ligand. 11. Comprises of methods of delivering pharmaceutical agents at higher concentrations to the desired part of the body. Professional writers in all subject areas are available and will meet your assignment deadline. Jonny-Ringo, first and foremost, loves to read and write. 2500 pages of free content are available only online. Topics: Chemistry, Mass spectrometry, Electron Pages: 204 (19197 words) Published: August 31, 2013. In drug design, steric shields are bulky groups added to metabolically vulnerable parts of the drug in order to slow down metabolism. 2. Refers to the extent by which orally administered drugs undergo biotransformation during its first passage through the liver and the intestines, reducing the concentration of the drug that reaches general circulation. In medicinal chemistry, transition state analogues are compounds that are designed to mimic an enzyme-catalysed reaction’s transition state. Abbreviation for Absorption, Distribution, Metabolism, Excretion.Sometimes referred to as ADMET or ADME-Tox to account for toxicity. calorimetry - Calorimetry is the study of heat flow. 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